Longevity · Longevity
Brain Aging & Dementia Prevention
What normal brain aging looks like, Alzheimer's biology (amyloid, tau, inflammation), the 14 modifiable risk factors (Lancet Commission 2024) that could prevent nearly half of dementia, and the new anti-amyloid drugs.
Step 1 of 6 · Overview30 min read ·
Key idea
Prereqs: Four horsemen; sleep. Next: Building a longevity plan. Sources: Livingston et al., Lancet Commission on dementia (2024); FINGER trial (Lancet 2015); Lisa Genova, *Remember* (2021); lecanemab CLARITY-AD (NEJM 2023).Next: 1. Normal vs disease